Recently, the research results published by Dr. Fangwei Qi and Dr. Youwen Yang, the backbone of the bio additive manufacturing team led by Professor cijun Shuai, were selected for the first time in ESI 1% highly cited papers. The research results published by Dr. Fangwei Qi is “Graphene oxide assists polyvinylidene fluoride scaffold to reconstruct electrical microenvironment of bone tissue, Mater Design，2020, 190: 108564.” The research results published by Dr. Youwen Yang is “Metal organic frameworks as a compatible reinforcement in a biopolymer bone scaffold, Mater Chem Front, 2020, 4(3): 973-984.”
Biopolymer bone scaffolds have problems such as insufficient mechanical strength and poor osteogenesis ability. For this reason, the research team proposed to introduce nanoparticles containing rich functional groups, such as graphene oxide and metal organic framework materials, into the polymer bone scaffold. The results show that the functional groups on the surface of the nanoparticles can form a good interface bond with the polymer matrix, which can improve the mechanical properties of the bone scaffold through mechanisms such as interface debonding and load transfer. More importantly, the nanoparticles can also induce the crystalline transformation of the piezoelectric polymer, thereby enhancing the piezoelectric activity of the bone scaffold and effectively promoting the proliferation and differentiation of osteoblasts. Professor Bingheng Lu, the father of 3D printing in China and academician of Chinese Academy of engineering, highly praised the series of research work. He believed that the prepared bone scaffold had appropriate mechanical strength, good biological performance and controllable degradation rate, which provided important scientific basis and technical support for the development and design of high-performance bone scaffold.
Paper link 1:
https://www.sciencedirect.com/science/article/pii/S0264127520300976?via%3Dihub
Paper link 2:
https://pubs.rsc.org/en/content/articlelanding/2020/QM/C9QM00772E#!divAbstract
